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IntroductionDuring pregnancy, women with Graves disease are at risk of maternal and fetal hyperthyroidism caused by stimulating TSH receptor antibody. Here we report the unusual case of a woman with recurrent Graves disease who developed central hypothyroidism transiently during pregnancy.Case report and resultsA 26-year-old woman was treated by antithyroid drug for a third episode of hyperthyroid...

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ea0070aep665 | Pituitary and Neuroendocrinology | ECE2020

Assessment of disease control in patients with acromegaly treated with long-acting somatostatin analogs (SMSa) varies according to the time when IGF-I levels are measured during the month following the injection

Cristina Albrici , Lecoq Anne-Lise , Vialon Magaly , Solange Grunenwald , Cocco Aldo , Hamdi Safouane , Vincenzo Cimino , Maione Luigi , Caron Philippe , Chanson Philippe

Introduction: Acromegaly is associated with multiple comorbidities and excess mortality. However, disease burden is reduced by maintaining IGF-1 (and/or GH) levels under safe levels. First generation long-acting SMSa, administered at monthly intervals, represent the first line medical treatment. According to guidelines, its efficacy is evaluated through IGF-I measurements. However, there are no data indicating the optimal time for measuring IGF-I levels after the SMSa injectio...

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Endocrine Abstracts

Central hypothyroidism during pregnancy in a woman with Graves’ disease

Assessment of disease control in patients with acromegaly treated with long-acting somatostatin analogs (SMSa) varies according to the time when IGF-I levels are measured during the month following the injection

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